Are Bio-IdenticalL Hormones Safe? The WHI study showed that synthetic, chemically altered hormones such as Provera cause cancer and heart disase. However, the bio-identical hormones do not cause increased breast cancer as shown in the French Cohort study published in Climacteric, Dec 2002. In addition a recent coronary calcium score study published in the NEJM June 2007, showed less calcification in the premarin only treated arm of the WHI, indicating protection from heart disease. The 2 arms of the WHI study suggest that the synthetic progestin, Provera is the culprit in the WHI study causing the increased risk of cancer and heart disease.
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